[Read.sZiK] Coronary Tone in Ischemic Heart Disease (Developments in Cardiovascular Medicine)
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W. KUPPER Coronary artery vasoconstriction is not only the mechanism responsible for Prinzmetal's variant angina, but may also be involved in stable angina pectoris and myocardial infarction. However, the underlying patho-physiological mecha nisms and the importance of coronary vasoconstriction in these syndromes is still largely unknown. Several hypotheses have been proposed. Sympathetic nervous activity plays a key role in the regulation of coronary blood flow, but mechanical or humoral constrictive factors may be active as well. a-adrenergic tone Adrenergic nerve fibers accompany coronary vessels of any size. The stimulation of cardiac sympathetic nerves causes an increase in coronary blood flow. If, however, chronotropic and inotropic effects of adrenergic stimulation are sup pressed pharmacologically by beta-adrenoceptor blockade, a reduction in flow is observed. Thus, the primary effect of sympathetic stimulation on the coronary arteries is the alpha-adrenergic mediated vasoconstriction. Functionally inner vated alpha-adrenoceptors have been documented both in large coronary con ductance arteries and in the small resistance vessels. Animal studies and a human study have documented that a permanent constrictor tone is present on the coronary circulation both at rest and during exercise; this condition could be prevented with alpha-adrenoceptor blockade or was absent after heart transplan tation. Therefore, alpha-adrenoceptor mediated coronary constriction is an at tractive hypothesis as a possible pathophysiological mechanism of inappropriate coronary vasoconstriction and cororiary vasospasm. News Archives from the Texas Heart Institute Archives of news from and about the Texas Heart Institute in 2011. Exercise Standards for Testing and Training Circulation The 2001 version of the exercise standards statement 1 has served effectively to reflect the basic fundamentals of ECGmonitored exercise testing and training of ... 2013 ACCF/AHA Guideline for the Management of ST-Elevation ... 2013 ACCF/AHA Guideline for the Management of ST-Elevation ... ... Preamble e364 Kawasaki disease - Wikipedia Kawasaki disease is a disease in which blood vessels throughout the body become inflamed. The most common symptoms include a fever that lasts for more than five days ... Inderal ** Buy Inderal ** Buy Cheap Inderal ** Propranolol ... Buy Propranolol Online! Buy Cheap Inderal online! Buy Propranolol online without leaving home! Buy Propranolol online overnight Inderal cheapest price! Primary Prevention of Cardiovascular Disease with a ... Original Article. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. Ramn Estruch M.D. Ph.D. Emilio Ros M.D. Ph.D. Jordi Salas-Salvad ... Erectile Dysfunction and Erection Problems: Causes ... Fast facts on erectile dysfunction. Here are some key points about erectile dysfunction. More detail and supporting information is in the body of this article. Atrial Fibrillation Treatment & Management: Approach ... Atrial fibrillation (AF) has strong associations with other cardiovascular diseases such as heart failure coronary artery disease (CAD) valvular heart disease ... Cardiology Online - International Academy of Cardiology Cardiology Online is a cardiology guide and directory for congresses meetings and publications on heart disease and heart failure of the International Academy of ... Coronary Artery Disease (CAD) CEU Wild Iris Medical Education INTRODUCTION. Coronary artery disease (CAD) is caused by atherosclerosis of the coronary arteries that leads to a restriction of blood flow to the heart.
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