Free Ebook BookElastic Filaments of the Cell (Advances in Experimental Medicine Biology (Springer))

[Free.fxqY] Elastic Filaments of the Cell (Advances in Experimental Medicine Biology (Springer))

[Free.fxqY] Elastic Filaments of the Cell (Advances in Experimental Medicine Biology (Springer))

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Elastic filaments refer mainly to titin, the largest of all known proteins. Titin was discovered initially in muscle cells, where it interconnects the thick filament with the Z-line. Titin forms a molecular spring that is responsible for maintaining the structural integrity of contracting muscle, ensuring efficient muscle contraction. More recently, it has become clear that titin is not restricted to muscle cells alone. For example, titin is found in chromosomes of neurons and also in blood platelets. This topic is fast becoming a focal point for research in understanding viscoelastic properties at the molecular, cellular, and tissue levels. In titin may lie a generic basis for biological viscoelasticity. It has become clear that titin may hold the key to certain clinical anomalies. For example, it is clear that titin-based ventricular stiffness is modulated by calcium and that titin is responsible for the altered stiffness in cardiomyopathies. It is also clear from evidence from a group of Finnish families that titin mutations may underlie some muscular dystrophies and that with other mutations chromatids fail to separate during mitosis. Thus, it is clear that this protein will have important clinical implications stemming from its biomechanical role. One aspect of this field is the bringing together of bioengineers with clinical researchers and biologists. Genetic and biochemical aspects of titin-related proteins are being studied together with front-line engineering approaches designed to measure the mechanics of titin either in small aggregates or in single molecules. nanocomputer.com - Nano-scale repairs at affordable cost First Nanotechnology Medicine Is Almost Here - The Libertarian Republic; Nanotechnology among us but regulators aren't doing enough to protect humans experts warn ... Resolve a DOI Name Type or paste a DOI name into the text box. Click Go. Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to doi ... Ideadiez.com is and in to a was not you i of it the be he his but for are this that by on at they with which she or from had we will have an what been one if would who has her ... Le Live Marseille : aller dans les plus grandes soires ... Retrouvez toutes les discothque Marseille et se retrouver dans les plus grandes soires en discothque Marseille. web.mit.edu / jik/src/Attic/kerberos_ password - . .mn 0 01 05_1 1 10 100 10th 11 11_d0003 12 13 14 141a 143b 15 16 17 17igp 18 19 1900 1901 1902 1903 1904 1905 1906 1907 1908 1909 1910 1911 1912 1913 1914 1915 ... Carbon nanotube - Wikipedia Carbon nanotubes (CNTs) are allotropes of carbon with a cylindrical nanostructure. These cylindrical carbon molecules have unusual properties which are valuable for ... Staphylococcus aureus Infections NEJM Review Article. Medical Progress. Staphylococcus aureus Infections. Franklin D. Lowy M.D. N Engl J Med 1998; 339:520-532 August 20 1998 DOI: 10.1056/NEJM199808203390806 5Web of Science Journal Title Abbreviations ... This list shows the abbreviations used for journal titles as cited works. Copy the abbreviated (boldface) title from this list and paste it in the Cited Work field on ... Mathematics Calendar - American Mathematical Society Mathematics Calendar. Questions and answers regarding this page can be sent to mathcal@ams.org. You can submit an entry to the Mathematics Calendar by filling out ...
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